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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. EIF2S2, Eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa
Sequence ID:NM_003908
Entrez Gene ID:8894
Ensembl ID:ENSG00000125977

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:20q11.2Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:20: 32691332 - 32700002

NM_003908 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
315973267611632677710
159816833267832232678407
168417403268148032681536
174118893268446232684610
189019903268522132685321
199121263268630332686438
212722303269126732691370
223124083269317332693350
240925923269990132700084

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
2822324Full LengthBC000461eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa
3447202Full LengthBC000934eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa
4120898Full LengthBC007888eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa
6727027IncompleteBC107588eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_003899  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_003908 NP_003899 P20042
Q6IBR8
eIF-5_eIF-2B

Related Sequences

 
mRNAGenPeptSwissProt
M29536 AAA52383 P20042
BC000461 AAH00461 P20042
Q6IBR8
BC000934 AAH00934 P20042
BC007888 AAH07888 Q96I16
BC107588 AAI07589 Q3B7I9
BT009795 AAP88797 P20042
Q6IBR8
DQ891005 ABM81931  
DQ894184 ABM85110  
AB208966 BAD92203 Q59GZ3
AK313025 BAG35860 Q6IBR8
AB451237 BAG70051 B5BU01
AB451362 BAG70176 B5BU01
CR456734 CAG33015 P20042
Q6IBR8

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens EIF2S2 NP_003899 R.norvegicus Eif2s2 296302   NP_955412 97
C.elegans iftb-1 172584   NP_492209 57
A.thaliana EIF2 BETA 832216   NP_197592 54
N.crassa NCU04640 3875321   XP_959183 50
S.cerevisiae SUI3 855838   NP_015087 49
S.pombe tif212 2542942   NP_593772 47

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta