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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. AIFM1, apoptosis-inducing factor, mitochondrion-associated, 1
Sequence ID:NM_001130846
NM_001130847
NM_004208
NM_145812
NM_145813
RefSeqGene ID:NG_013217
Entrez Gene ID:9131
Ensembl ID:ENSG00000156709

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, placenta, pooled tissue, prostate, retina, skin, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:Xq26.1Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:X: 129263509 - 129299672

 Exon Info From UCSC:
NM_001130846
NM_001130847
NM_004208
NM_145812
NM_145813

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
5767978Full LengthBC111065apoptosis-inducing factor, mitochondrion-associated, 1
40085139Full LengthBC139738apoptosis-inducing factor, mitochondrion-associated, 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_665811  NP_004199  NP_665812  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_001130846 NP_001124318    
NM_001130847 NP_001124319    
NM_004208 NP_004199 O95831 Pyr_redox
Pyr_redox_2
NM_145812 NP_665811   Pyr_redox
Pyr_redox_2
NM_145813 NP_665812   Pyr_redox
Pyr_redox_2

Related Sequences

 
mRNAGenPeptSwissProt
AF100928 AAD16436 O95831
AF131759 AAD20036 O95831
BC111065 AAI11066 O95831
BC139738 AAI39739 O95831
AY795556 AAV54053 Q5RZA0
AY795557 AAV54054 Q5RZ99
DQ016496 AAY84737 Q2QKE4
DQ016498 AAY84739 O95831
DQ016500 AAY84741 Q1L6K4
AK314446 BAG37055 O95831
AL049703 CAB41267 O95831
AL049704 CAB41268 O95831
CR457379 CAG33660 O95831

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens AIFM1 NP_004199 R.norvegicus Aifm1 83533   NP_112646 93
M.musculus Aifm1 26926 Gene Info NP_036149 92
A.gambiae AgaP_AGAP008044 1277908   XP_317418 53
D.melanogaster AIF 33390   NP_608649 50
C.elegans wah-1 176635   NP_499564 41

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta