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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. SIRT6, sirtuin 6
Sequence ID:NM_001193285
Entrez Gene ID:51548
Ensembl ID:ENSG00000077463

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

Cytogenetic Location (from UniGene)

Cytogenetic Location:19p13.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:19: 4174105 - 4182596

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
2820472Full LengthBC005026sirtuin (silent mating type information regulation 2 homolog) 6 (S. cerevisiae)
3352203Full LengthBC004218sirtuin (silent mating type information regulation 2 homolog) 6 (S. cerevisiae)
5217599Full LengthBC028220sirtuin (silent mating type information regulation 2 homolog) 6 (S. cerevisiae)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_057623  

Protein Infomation

NM_001193285 NP_001180214    
NM_016539 NP_057623 Q8N6T7 SIR2

Related Sequences

AF233396 AAF43432 Q8N6T7
BC004218 AAH04218 Q8N6T7
BC005026 AAH05026 Q8N6T7
BC028220 AAH28220 Q8N6T7
DQ896358 ABM87357  
EU176413 ABW03864  
AK074810 BAC11222 Q8N6T7
AK315048 BAG37527 Q8N6T7
AK293348 BAG56864 B4DDV3
AK301247 BAG62814 B4DVV2
AK299420 BAH13027 B7Z5U1
CR457200 CAG33481 Q8N6T7

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens SIRT6 NP_057623 R.norvegicus Sirt6 299638   NP_001026819 89
M.musculus Sirt6 50721 Gene Info NP_853617 89
A.gambiae AgaP_AGAP001458 1281717   XP_321669 58
D.melanogaster Sirt6 41254   NP_649990 53
A.thaliana SRT1 835670   NP_200387 52
N.crassa NCU07624 3878947   XP_962799 43

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)