Skip Navigation
NCI banner National Cancer Institute U.S. National Institutes of Health National Cancer Institute
Genes
  • Gene Tools
Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. GAD1, glutamate decarboxylase 1 (brain, 67kDa)
Sequence ID:NM_000817
NM_013445
RefSeqGene ID:NG_021477
Entrez Gene ID:2571
Ensembl ID:ENSG00000128683

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
CEREBRAL PALSY, SPASTIC QUADRIPLEGIC, 1 

Cytogenetic Location (from UniGene)

Cytogenetic Location:2q31Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:2: 171675101 - 171699269

 Exon Info From UCSC:
NM_000817
NM_013445

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4794214Full LengthBC026349glutamate decarboxylase 1 (brain, 67kDa)
5264831Full LengthBC036552glutamate decarboxylase 1 (brain, 67kDa)
5273792Full LengthBC037780glutamate decarboxylase 1 (brain, 67kDa)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000808  NP_038473  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_000817 NP_000808 Q99259 EC 4.1.1.15 Pyridoxal_deC
NM_013445 NP_038473     Pyridoxal_deC

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
M70434 AAA52512 Q99259 EC 4.1.1.15
M81883 AAA62368 Q99259 EC 4.1.1.15
M55574 AAA72938 Q99259 EC 4.1.1.15
S61897 AAB26937 Q99259 EC 4.1.1.15
S61898 AAB26938 Q99259 EC 4.1.1.15
L16888 AAB59427 Q99259 EC 4.1.1.15
AF178853 AAF18390 Q99259 EC 4.1.1.15
BC002815 AAH02815 Q99259 EC 4.1.1.15
BC026349 AAH26349 Q99259 EC 4.1.1.15
BC036552 AAH36552 Q49AK1  
BC037780 AAH37780 Q8IVA8  
DQ892376 ABM83302    
DQ895590 ABM86516    
AK292582 BAF85271 A8K967  
A28074 CAA01913 Q99259 EC 4.1.1.15
Z22750 CAA80435 Q99259 EC 4.1.1.15

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens GAD1 NP_000808 M.musculus Gad1 14415 Gene Info NP_032103 97
R.norvegicus Gad1 24379   NP_058703 97
D.melanogaster Gad1 38484   NP_523914 59
A.gambiae AgaP_AGAP005866 1276534   XP_315894 57
C.elegans unc-25 176713   NP_499689 57
N.crassa NCU06112 3876112   XP_959974 37

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)