Skip Navigation
NCI banner National Cancer Institute U.S. National Institutes of Health National Cancer Institute
Genes
  • Gene Tools
Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. TCN2, transcobalamin II
Sequence ID:NM_000355
NM_001184726
NM_001190420
RefSeqGene ID:NG_007263
Entrez Gene ID:6948
Ensembl ID:ENSG00000185339

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
TRANSCOBALAMIN II DEFICIENCY 

Cytogenetic Location (from UniGene)

Cytogenetic Location:22q12.2Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:22: 31003273 - 31024451

 Exon Info From UCSC:
NM_000355
NM_001184726
NM_001190420

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3353271Full LengthBC001176transcobalamin II; macrocytic anemia
4153362Full LengthBC011239transcobalamin II; macrocytic anemia

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000346  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_000355 NP_000346 P20062 Cobalamin_bind
NM_001184726 NP_001171655    

Related Sequences

 
mRNAGenPeptSwissProt
M60396 AAA61054 P20062
L02647 AAA61056 P20062
L02648 AAA61057 P20062
BC001176 AAH01176 P20062
BC011239 AAH11239 P20062
DQ892811 ABM83737  
DQ896057 ABM87056  
CR456591 CAG30477 P20062
CU013191 CAK54622  
CU013479 CAK54921  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens TCN2 NP_000346 R.norvegicus Tcn2 64365   NP_071979 75
M.musculus Tcn2 21452 Gene Info NP_001123930 74

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)