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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. MSTN, myostatin
Sequence ID:NM_005259
RefSeqGene ID:NG_009800
Entrez Gene ID:2660
Ensembl ID:ENSG00000138379

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data


Cytogenetic Location (from UniGene)

Cytogenetic Location:2q32.2Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:2: 190921983 - 190927322

NM_005259 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
61943190920426190922363
19442317190924787190925160
23182823190926949190927454

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
30915216Full LengthBC074757myostatin

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_005250  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_005259 NP_005250 O14793
Q53S46
TGF_beta
TGFb_propeptide

Related Sequences

 
mRNAGenPeptSwissProt
AF019627 AAB86694 O14793
Q53S46
AF104922 AAC96327 O14793
Q53S46
BC074757 AAH74757 O14793
Q53S46
EU446953 ABZ92482  
AK291524 BAF84213 Q53S46

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens MSTN NP_005250 M.musculus Mstn 17700 Gene Info NP_034964 96
R.norvegicus Mstn 29152   NP_062024 95
D.melanogaster myoglianin 43811   NP_726606 36

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)