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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. SERPINE1, serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
Sequence ID:NM_000602
NM_001165413
RefSeqGene ID:NG_013213
Entrez Gene ID:5054
Ensembl ID:ENSG00000106366

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
PLASMINOGEN ACTIVATOR INHIBITOR-1 DEFICIENCY 

Cytogenetic Location (from UniGene)

Cytogenetic Location:7q22.1Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:7: 100770383 - 100781375

 Exon Info From UCSC:
NM_000602
NM_001165413

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3893914Full LengthBC010860serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000593  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_000602 NP_000593 P05121 Serpin
NM_001165413 NP_001158885    

Related Sequences

 
mRNAGenPeptSwissProt
M16006 AAA60003 P05121
M14083 AAA60008 P05121
BC010860 AAH10860 P05121
DQ890694 ABM81620  
DQ893877 ABM84803  
AK293248 BAH11475 B7Z1D9
AK297728 BAH12656 B7Z4S0
AK298048 BAH12712 B7Z4X6
AK316225 BAH14596 B7ZAB0
X04429 CAA28025 P05121
X04729 CAA28438 P05121
X04731 CAA28442 P05121
X04744 CAA28444 P05121
X12701 CAA31208 P05121

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens SERPINE1 NP_000593 R.norvegicus Serpine1 24617   NP_036752 81
M.musculus Serpine1 18787 Gene Info NP_032897 79
A.gambiae SRPN1 1270171   XP_308847 32

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta