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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. RAC1, Ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
Sequence ID:NM_018890
NM_006908
RefSeqGene ID:NG_029431
Entrez Gene ID:5879
Ensembl ID:ENSG00000136238

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:7p22Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:7: 6414178 - 6436667

 Exon Info From UCSC:
NM_018890
NM_006908

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3610745Full LengthBC004247ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
6149377Full LengthBC050687ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
6699945Full LengthBC107748ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_008839  NP_061485  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_006908 NP_008839 P63000 Ras
NM_018890 NP_061485   Ras
Miro

Related Sequences

 
mRNAGenPeptSwissProt
M29870 AAA36537 P63000
M31467 AAA36544 P63000
AF136373 AAD30547 P63000
BC004247 AAH04247 P63000
BC050687 AAH50687 P63000
BC107748 AAI07749 P63000
AF498964 AAM21111 P63000
BT007121 AAP35785 P63000
AY279384 AAQ16632 P63000
EU832058 ACE86720  
EU832717 ACE87049  
EU831965 ACE87406  
EU832640 ACE87731  
AB209410 BAD92647 Q59FQ0
AK291806 BAF84495 A4D2P1
AK291815 BAF84504 A4D2P0
AK054993 BAG51447 A4D2P1
AB451238 BAG70052 A4D2P1
AB451363 BAG70177 A4D2P1
AJ132694 CAA10732 P63000

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens RAC1 NP_061485 M.musculus Rac1 19353 Gene Info NP_033033 100
R.norvegicus Rac1 363875   NP_599193 100
D.melanogaster Rac2 38831   NP_648121 90
N.crassa NCU02160 3880671   XP_964519 77
A.thaliana RAC3 829654   NP_001190916 68
A.thaliana ARAC1 816290   NP_001077910 67
A.thaliana ROP1 824293   NP_190698 66
A.thaliana RAC6 829750   NP_195320 66

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta