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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. PLCG2, phospholipase C, gamma 2 (phosphatidylinositol-specific)
Sequence ID:NM_002661
RefSeqGene ID:NG_032019
Entrez Gene ID:5336
Ensembl ID:ENSG00000197943

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Cytogenetic Location (from UniGene)

Cytogenetic Location:16q24.1Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:16: 81812906 - 81991898

 Exon Info From UCSC:
NM_002661

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
2989125Full LengthBC007565phospholipase C, gamma 2 (phosphatidylinositol-specific)
2989281Full LengthBC014561phospholipase C, gamma 2 (phosphatidylinositol-specific)
2989389Full LengthBC018646phospholipase C, gamma 2 (phosphatidylinositol-specific)
3678272Full LengthBC011772phospholipase C, gamma 2 (phosphatidylinositol-specific)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_002652  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_002661 NP_002652 P16885 EC 3.1.4.11 SH2
SH3_1
C2
PH
PI-PLC-Y
PI-PLC-X

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
M37238 AAA60112 P16885 EC 3.1.4.11
BC007565 AAH07565 P16885 EC 3.1.4.11
BC011772 AAH11772 P16885 EC 3.1.4.11
BC014561 AAH14561 P16885 EC 3.1.4.11
BC018646 AAH18646 P16885 EC 3.1.4.11
AY364256 AAQ76815 P16885 EC 3.1.4.11
DQ893524 ABM84450    
DQ896514 ABM87513    
AB208914 BAD92151 P16885 EC 3.1.4.11
AK304722 BAG65485 B4E3H3  
X14034 CAA32194 P16885 EC 3.1.4.11

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens PLCG2 NP_002652 R.norvegicus Plcg2 29337   NP_058864 95
M.musculus Plcg2 234779 Gene Info NP_758489 94

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)