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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. HPRT1, Hypoxanthine phosphoribosyltransferase 1
Sequence ID:NM_000194
RefSeqGene ID:NG_012329
Entrez Gene ID:3251
Ensembl ID:ENSG00000165704

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
HPRT-RELATED GOUT 
LESCH-NYHAN SYNDROME 

Cytogenetic Location (from UniGene)

Cytogenetic Location:Xq26.1Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:X: 133594194 - 133634107

NM_000194 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
1194133594174133594367
195301133607388133607494
302485133609210133609393
486551133620494133620559
552569133624217133624234
570652133627537133627619
653699133632419133632465
700776133632637133632713
7771413133634059133634695

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3163726Full LengthBC000578hypoxanthine phosphoribosyltransferase 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000185  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_000194 NP_000185 P00492 EC 2.4.2.8 Pribosyltran

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
M31642 AAA52690 P00492 EC 2.4.2.8
L29383 AAB59391 P00492 EC 2.4.2.8
L29382 AAB59392 P00492 EC 2.4.2.8
S60300 AAC60591 P00492 EC 2.4.2.8
BC000578 AAH00578 P00492 EC 2.4.2.8
BT019350 AAV38157 P00492 EC 2.4.2.8
DQ895107 ABM86033    
DQ895109 ABM86035    
EU176655 ABW03456    
EU176316 ABW03767    
AK313435 BAG36226 P00492 EC 2.4.2.8
CR407645 CAG28573 Q6LET3  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens HPRT1 NP_000185 M.musculus Hprt 15452 Gene Info NP_038584 97
R.norvegicus Hprt1 24465   NP_036715 95
P.falciparum PF10_0121 810279   XP_001347406 50
C.elegans Y105E8B.5 173323   NP_493545 49

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)