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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. GDF1, growth differentiation factor 1
Sequence ID:NM_001492
RefSeqGene ID:NG_012070
Entrez Gene ID:2657
Ensembl ID:ENSG00000130283

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
CONOTRUNCAL ANOMALY FACE SYNDROMECFC1
GATA6
GATA6
NKX2-5
NKX2-6
TBX1
TETRALOGY OF FALLOTGATA6
GATA6
JAG1
JAG1
NKX2-5
ZFPM2

Cytogenetic Location (from UniGene)

Cytogenetic Location:19p12Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:19: 18980842 - 18990059

NM_001492 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
18391897936018980198
84014761898079118981427
147715861898973818989847
158717341899004918990196
173518961899108218991243
189720771899489518995075
207822371900422419004383
223825581900663219006952

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
6192817Full LengthBC084582LAG1 homolog, ceramide synthase 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_001483  NP_067090  NP_937850  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_001492 NP_001483 P27539 TGF_beta
NM_021267 NP_067090 P27544 LAG1
NM_198207 NP_937850   LAG1

Related Sequences

 
mRNAGenPeptSwissProt
M62302 AAA58500 P27544
M62302 AAA58501 P27539
BC084582 AAH84582 Q5XG75
AB209169 BAD92406 Q59GE0

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens GDF1 NP_001483 R.norvegicus Gdf1 306351   NP_001037705 73
M.musculus Gdf1 14559 Gene Info NP_001156754 72

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)