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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. ITGA2B, integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
Sequence ID:NM_000419
RefSeqGene ID:NG_008331
Entrez Gene ID:3674
Ensembl ID:ENSG00000005961

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
GLANZMANN THROMBASTHENIAITGB3

Cytogenetic Location (from UniGene)

Cytogenetic Location:17q21.32Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:17: 42452714 - 42454388

 Exon Info From UCSC:
NM_000419

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
8992158Full LengthBC126442integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
40125994Full LengthBC117443integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000410  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_000419 NP_000410 P08514 Integrin_alpha
FG-GAP
Integrin_alpha2

Related Sequences

 
mRNAGenPeptSwissProt
M34480 AAA35926 P08514
M18085 AAA52597 P08514
J02764 AAA60114 P08514
AF098114 AAC98507 P08514
BC117443 AAI17444 P08514
BC126442 AAI26443 P08514
DQ841705 ABI15196 Q0MVN7
AB209552 BAD92789 Q59FA8
AK315335 BAG37735 P08514
AK297155 BAG59654 B4DLU2
AK303081 BAH13896 B7Z8B0
X06831 CAA29987 P08514

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens ITGA2B NP_000410 M.musculus Itga2b 16399 Gene Info NP_034705 81
R.norvegicus Itga2b 685269   XP_001063315 79

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)