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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. EIF2B2, eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa
Sequence ID:NM_014239
RefSeqGene ID:NG_013333
Entrez Gene ID:8892
Ensembl ID:ENSG00000119718

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
LEUKOENCEPHALOPATHY WITH VANISHING WHITE MATTEREIF2B1
EIF2B3
EIF2B4
EIF2B5

Cytogenetic Location (from UniGene)

Cytogenetic Location:14q24.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:14: 75469647 - 75476292

NM_014239 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
12457546961175469855
2463667546997775470097
3675157547025375470401
5166797547143975471602
6807757547256875472663
7769137547327975473416
9149807547442475474490
98115407547573375476292

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
2820668Full LengthBC000494eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa
2820668Full LengthBC003165eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa
3534548Full LengthBC011750eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_055054  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_014239 NP_055054 P49770
Q53XC2
IF-2B

Related Sequences

 
mRNAGenPeptSwissProt
AF035280 AAB88176 P49770
Q53XC2
L40395 AAC42002 P49770
BC000494 AAH00494 Q9BPX4
BC003165 AAH03165 Q9BPX4
BC011750 AAH11750 P49770
Q53XC2
DQ891364 ABM82290  
DQ894544 ABM85470  
BX161473 CAD61929 P49770
Q53XC2

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens EIF2B2 NP_055054 M.musculus Eif2b2 217715 Gene Info NP_663420 94
R.norvegicus Eif2b2 84005   NP_114447 94
A.gambiae AgaP_AGAP007097 1270006   XP_308661 51
D.melanogaster eIF2B-beta 31256   NP_570020 50
S.pombe SPAC343.14c 2543035   NP_593435 44
S.cerevisiae GCD7 850998   NP_013394 36

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta