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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. FEN1, flap structure-specific endonuclease 1
Sequence ID:NM_004111
Entrez Gene ID:2237
Ensembl ID:ENSG00000168496

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, placenta, pooled tissue, prostate, retina, salivary gland, skin, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:11q12Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:11: 61560376 - 61564146

NM_004111 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
2821792Full LengthBC000323flap structure-specific endonuclease 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_004102  

Protein Infomation

NM_004111 NP_004102 P39748

Related Sequences

L37374 AAA91331 P39748
BC000323 AAH00323 P39748
BT019524 AAV38331 P39748
AK312761 BAG35627 Q6FHX6
AK301743 BAG63206 B4DWZ4
X76771 CAA54166 P39748
CR536562 CAG38799 P39748

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens FEN1 NP_004102 M.musculus Fen1 14156 Gene Info NP_032025 97
R.norvegicus Fen1 84490   NP_445882 96
A.gambiae AgaP_AGAP011448 1278246   XP_317855 64
D.melanogaster Fen1 36887   NP_523765 64
C.elegans crn-1 171917   NP_491168 63
S.cerevisiae RAD27 853747   NP_012809 60
A.thaliana AT5G26680 832721   NP_001154740 56
S.pombe rad2 2543164   NP_594972 56
N.crassa NCU10776 5847646   XP_001728355 55
P.falciparum FEN-1 812356   XP_001351399 47

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)