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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. C2, complement component 2
Sequence ID:NM_000063
NM_001145903
NM_001178063
NR_073063
RefSeqGene ID:NG_011730
Entrez Gene ID:717
Ensembl ID:ENSG00000166278

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
AGE-RELATED MACULOPATHYAPOE
CFB
CFHR1
CFHR3
CX3CR1
HMCN1
PLEKHA1
PLEKHA1
TLR3
C2 DEFICIENCY 

Cytogenetic Location (from UniGene)

Cytogenetic Location:6p21.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:6: 31865563 - 31913446

 Exon Info From UCSC:
NM_000063
NM_001145903
NM_001178063

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
5763774Full LengthBC043484complement component 2

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000054  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_000063 NP_000054 Q5JP69
P06681
EC 3.4.21.43 Sushi
Trypsin
VWA
NM_001145903 NP_001139375      
NM_001178063 NP_001171534      

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
BC029781 AAH29781 Q8N6L6  
BC043484 AAH43484 Q5JP69
P06681
EC 3.4.21.43
AK222537 BAD96257 Q53HP3  
AK222783 BAD96503 Q53GZ8  
AK312581 BAG35475 Q5JP69  
AK096258 BAG53241 B3KTX9  
AK298311 BAG60565 P06681 EC 3.4.21.43
AK298808 BAG60943 B4DQI1  
AK300892 BAG62532 B4DV20  
AK300930 BAG62560 B4DV48  
X04481 CAA28169 P06681 EC 3.4.21.43
BX537504 CAD97767 Q7Z685  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens C2 NP_000054 R.norvegicus C2 24231   NP_757376 78
M.musculus C2 12263 Gene Info NP_038512 76

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta