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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. SPINK1, serine peptidase inhibitor, Kazal type 1
Sequence ID:NM_003122
RefSeqGene ID:NG_008356
Entrez Gene ID:6690
Ensembl ID:ENSG00000164266

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
FIBROCALCULOUS PANCREATICDIABETES 
PANCREATITIS, CHRONIC, PROTECTION AGAINSTCFTR
CFTR
CFTR
CTRC
PRSS1
PRSS2
PRSS2
PRSS2

Cytogenetic Location (from UniGene)

Cytogenetic Location:5q32Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:5: 147204145 - 147211155

NM_003122 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
14140147204142147204268
141247147207584147207690
248279147209161147209192
280454147211085147211259

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
5225693Full LengthBC025790serine peptidase inhibitor, Kazal type 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_003113  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_003122 NP_003113 P00995 Kazal_1

Related Sequences

 
mRNAGenPeptSwissProt
M11949 AAA36521 P00995
BC025790 AAH25790 P00995
DQ893613 ABM84539  
DQ896842 ABM87841  
Y00705 CAA68697 P00995

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens SPINK1 NP_003113 M.musculus Spink3 20730 Gene Info NP_033284 70
R.norvegicus Spink1 266602   NP_690919 67
R.norvegicus Spink3 24833   NP_036806 63

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)