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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. FKBP5, FK506 binding protein 5
Sequence ID:NM_001145775
NM_001145776
NM_001145777
NM_004117
RefSeqGene ID:NG_012645
Entrez Gene ID:2289
Ensembl ID:ENSG00000096060

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, pituitary gland, placenta, pooled tissue, prostate, skin, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes
MAJOR DEPRESSIVE DISORDER, RESPONSE TO CITALOPRAM THERAPY INHTR2A
TPH2

Cytogenetic Location (from UniGene)

Cytogenetic Location:6p21.31Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:6: 35548333 - 35656631

 Exon Info From UCSC:
NM_001145775
NM_001145776
NM_001145777
NM_004117

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4539929Full LengthBC042605FK506 binding protein 5
5723416Full LengthBC111050FK506 binding protein 5

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_004108  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_001145775 NP_001139247      
NM_001145776 NP_001139248      
NM_001145777 NP_001139249      
NM_004117 NP_004108 Q13451 EC 5.2.1.8 FKBP_C
TPR_1

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
U42031 AAA86245 Q13451 EC 5.2.1.8
U71321 AAC51189 Q13451 EC 5.2.1.8
BC042605 AAH42605 Q13451 EC 5.2.1.8
BC111050 AAI11051 Q2TA84  
AF194172 AAL54872 Q13451 EC 5.2.1.8
AB209893 BAD93130 Q59EB8  
AK222807 BAD96527 Q53GX4  
AK312422 BAG35332 Q13451 EC 5.2.1.8
AK302704 BAH13784 B7Z7Z8  
AK303356 BAH13948 B7Z8G2  
AM393744 CAL38619    

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens FKBP5 NP_004108 R.norvegicus Fkbp5 361810   NP_001012174 91
M.musculus Fkbp5 14229 Gene Info NP_034350 87
A.thaliana ROF1 822117   NP_189160 37

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)