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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. HSD17B4, hydroxysteroid (17-beta) dehydrogenase 4
Sequence ID:NM_000414
RefSeqGene ID:NG_008182
Entrez Gene ID:3295
Ensembl ID:ENSG00000133835

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pineal gland, pituitary gland, placenta, pooled tissue, prostate, retina, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:5q21Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:5: 118788447 - 118878027

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3502915Full LengthBC003098hydroxysteroid (17-beta) dehydrogenase 4

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000405  

Protein Infomation

NM_000414 NP_000405 P51659 EC
EC 1.1.1.n12
NM_001199291 NP_001186220      
NM_001199292 NP_001186221      

Related Sequences

BC003098 AAH03098 P51659 EC
EC 1.1.1.n12
DQ891866 ABM82792    
DQ895055 ABM85981    
AK312449 BAG35356 B2R659  
AK094049 BAG52804 B3KSP2  
AK293254 BAG56786 B4DDM5  
AK295440 BAG58380 B4DI68  
AK298075 BAG60363 B4DNV1  
AK299685 BAG61592 B4DSD0  
AK301212 BAG62787 B4DVS5  
X87176 CAA60643 P51659 EC
EC 1.1.1.n12

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens HSD17B4 NP_000405 R.norvegicus Hsd17b4 79244   NP_077368 87
M.musculus Hsd17b4 15488 Gene Info NP_032318 86
D.melanogaster CG3415 32582   NP_573109 55
A.gambiae AgaP_AGAP008667 1275515   XP_314766 54
C.elegans dhs-28 180950   NP_509146 51
N.crassa NCU08828 3878199   XP_962039 50
A.thaliana ECH2 843947   NP_177742 43
S.cerevisiae FOX2 853878   NP_012934 43

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta