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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. HIBADH, 3-hydroxyisobutyrate dehydrogenase
Sequence ID:NM_152740
Entrez Gene ID:11112
Ensembl ID:ENSG00000106049

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, bone marrow, brain, cartilage, cerebrum, cervix, colon, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:7p15.2Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:7: 27565060 - 27702494

NM_152740 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
169472756505927565990
94811042757081027570966
110511812757795927578035
118213152758258527582718
131614372766898927669110
143815472767195427672063
154817082768909127689251
170920122770231627702619

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3890576Full LengthBC0323243-hydroxyisobutyrate dehydrogenase
3529287IncompleteBC0201673-hydroxyisobutyrate dehydrogenase

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_689953  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_152740 NP_689953 Q546Z2
P31937
EC 1.1.1.31 NAD_binding_2

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
BC032324 AAH32324 Q546Z2
P31937
EC 1.1.1.31
AF529362 AAQ09596 Q546Z2
P31937
EC 1.1.1.31
DQ894677 ABM85603    
AB050000 BAF42045 Q546Z2  
AK316605 BAG38192 Q546Z2  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens HIBADH NP_689953 M.musculus Hibadh 58875 Gene Info NP_663542 91
R.norvegicus Hibadh 63938   NP_071579 91
C.elegans B0250.5 180344   NP_507943 55
A.gambiae AgaP_AGAP005581 1276267   XP_315590 53
A.thaliana AT4G20930 827841   NP_567617 52
D.melanogaster CG15093 37166   NP_725824 48
N.crassa NCU06559 3878424   XP_962266 45

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)