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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. NTRK1, neurotrophic tyrosine kinase, receptor, type 1
Sequence ID:NM_001007792
NM_001012331
NM_002529
RefSeqGene ID:NG_007493
Entrez Gene ID:4914
Ensembl ID:ENSG00000198400

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
INSENSITIVITY TO PAIN, CONGENITAL, WITH ANHIDROSIS 
MEDULLARY THYROID CARCINOMA, FAMILIALRET

Cytogenetic Location (from UniGene)

Cytogenetic Location:1q21-q22Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:1: 156785470 - 156851641

 Exon Info From UCSC:
NM_001007792
NM_001012331
NM_002529

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
9020544Full LengthBC136554neurotrophic tyrosine kinase, receptor, type 1
9052759Full LengthBC144239neurotrophic tyrosine kinase, receptor, type 1
5200930IncompleteBC062580neurotrophic tyrosine kinase, receptor, type 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_001012331  NP_002520  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_001007792 NP_001007793      
NM_001012331 NP_001012331     Pkinase_Tyr
NM_002529 NP_002520 P04629 EC 2.7.10.1 Pkinase_Tyr

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
M23102 AAA36770 P04629 EC 2.7.10.1
BC062580 AAH62580 P04629 EC 2.7.10.1
BC136554 AAI36555 P04629 EC 2.7.10.1
BC144239 AAI44240 P04629 EC 2.7.10.1
AK290759 BAF83448 A8K3Z4  
AK312704 BAG35582 P04629 EC 2.7.10.1

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens NTRK1 NP_002520 M.musculus Ntrk1 18211 Gene Info NP_001028296 87
R.norvegicus Ntrk1 59109   NP_067600 87

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta