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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. ADAM17, ADAM metallopeptidase domain 17
Sequence ID:NM_003183
RefSeqGene ID:NG_029873
Entrez Gene ID:6868
Ensembl ID:ENSG00000151694

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Cytogenetic Location (from UniGene)

Cytogenetic Location:2p25Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:2: 9666274 - 9695884

 Exon Info From UCSC:
NM_003183

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
9020773Full LengthBC136783ADAM metallopeptidase domain 17

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_003174  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_003183 NP_003174 P78536 EC 3.4.24.86 Disintegrin
Reprolysin

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
U69611 AAB51514 P78536 EC 3.4.24.86
U86755 AAB51586 P78536 EC 3.4.24.86
U69612 AAB53014 P78536 EC 3.4.24.86
U92649 AAC39721 P78536 EC 3.4.24.86
BC062687 AAH62687 Q6P5T8  
BC136783 AAI36784 B2RNB2  
BC146658 AAI46659 A6H8L4  
GQ402545 ACV30013 B2RNB2  
AK289829 BAF82518 A8K1B4  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens ADAM17 NP_003174 R.norvegicus Adam17 57027   NP_064702 92
M.musculus Adam17 11491 Gene Info NP_033745 92
A.gambiae AgaP_AGAP002381 1273579   XP_312572 48
D.melanogaster Tace 43558   NP_733334 45
C.elegans adm-4 181041   NP_509318 37

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta