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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. GARS, glycyl-tRNA synthetase
Sequence ID:NM_002047
RefSeqGene ID:NG_007942
Entrez Gene ID:2617
Ensembl ID:ENSG00000106105

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pineal gland, pituitary gland, placenta, pooled tissue, prostate, retina, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes
CHARCOT-MARIE-TOOTH DISEASE, TYPE 2D 
NEUROPATHY, DISTAL HEREDITARY MOTOR, TYPE VBSCL2

Cytogenetic Location (from UniGene)

Cytogenetic Location:7p15Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:7: 30634447 - 30673643

 Exon Info From UCSC:
NM_002047

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4109682Full LengthBC007755glycyl-tRNA synthetase
4299853Full LengthBC007722glycyl-tRNA synthetase

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_002038  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_002047 NP_002038 P41250 EC 6.1.1.14 WHEP-TRS
tRNA-synt_2b
HGTP_anticodon

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
U09587 AAA57001 P41250 EC 6.1.1.14
U09510 AAA86443 P41250 EC 6.1.1.14
BC007722 AAH07722 P41250 EC 6.1.1.14
BC007755 AAH07755 P41250 EC 6.1.1.14
DQ892773 ABM83699    
DQ896021 ABM87020    
D30658 BAA06338 P41250 EC 6.1.1.14
AK074524 BAG51964 P41250 EC 6.1.1.14
AK295490 BAG58412 P41250 EC 6.1.1.14

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens GARS NP_002038 M.musculus Gars 353172 Gene Info NP_851009 93
R.norvegicus Gars 297113   XP_216152 93
A.gambiae AgaP_AGAP008604 1275455   XP_557743 64
D.melanogaster Aats-gly 39644   NP_730022 60
C.elegans grs-1 175703   NP_498093 58
N.crassa NCU00405 3873413   XP_957291 53
S.pombe grs1 2543181   NP_593935 51
A.thaliana AT1G29880 839866   NP_564337 51
S.cerevisiae GRS1 852418   NP_009679 50
P.falciparum PF14_0198 811779   XP_001348371 46

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)