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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. SUFU, suppressor of fused homolog (Drosophila)
Sequence ID:NM_001178133
NM_016169
RefSeqGene ID:NG_021338
Entrez Gene ID:51684
Ensembl ID:ENSG00000107882

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
MEDULLOBLASTOMAABR
APC
APC
BRCA2
CTNNB1
DMBT1
PTCH1
PTCH2
MENINGIOMAMN1
NF2
PTEN

Cytogenetic Location (from UniGene)

Cytogenetic Location:10q24.32Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:10: 104263763 - 104379218

 Exon Info From UCSC:
NM_001178133
NM_016169

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3533158Full LengthBC013291suppressor of fused homolog (Drosophila)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_057253  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_001178133 NP_001171604    
NM_016169 NP_057253 Q9UMX1 SUFU

Related Sequences

 
mRNAGenPeptSwissProt
AF175770 AAD50501 Q9UMX1
AF172319 AAD51655 Q9UMX1
AF144231 AAF23890 Q9UMX1
AF159447 AAF23893 Q9UMX1
AF222345 AAF35866 Q9UMX1
BC013291 AAH13291 Q9UMX1
AY358550 AAQ88914 Q9UMX1
DQ892586 ABM83512  
DQ895804 ABM86730  
AK312319 BAG35241 B2R5U4
AL137465 CAB70752 Q9UMX1

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens SUFU NP_057253 M.musculus Sufu 24069 Gene Info NP_056567 98
R.norvegicus Sufu 361769   NP_001020070 98
A.gambiae AgaP_AGAP001948 1281176   XP_321114 48
D.melanogaster Su(fu) 41565   NP_536750 41

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta