Skip Navigation
NCI banner National Cancer Institute U.S. National Institutes of Health National Cancer Institute
  • Gene Tools
Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. PPP2R4, protein phosphatase 2A activator, regulatory subunit 4
Sequence ID:NM_001193397
RefSeqGene ID:NG_029370
Entrez Gene ID:5524
Ensembl ID:ENSG00000119383

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, salivary gland, skin, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:9q34Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:9: 131905344 - 131907015

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3138990Full LengthBC002545protein phosphatase 2A activator, regulatory subunit 4
3140067Full LengthBC011605protein phosphatase 2A activator, regulatory subunit 4
3447497IncompleteBC010497protein phosphatase 2A, regulatory subunit B' (PR 53)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_821070  NP_066954  NP_821068  NP_821067  

Protein Infomation

NM_001193397 NP_001180326      
NM_001271832 NP_001258761      
NM_021131 NP_066954     PTPA
NM_178000 NP_821067     PTPA
NM_178001 NP_821068 Q15257 EC PTPA
NM_178003 NP_821070     PTPA

Related Sequences

BC002545 AAH02545 Q15257 EC
BC011605 AAH11605 Q15257 EC
BT020119 AAV38922 Q15257 EC
DQ892154 ABM83080    
DQ894879 ABM85805    
DQ895349 ABM86275    
AK222788 BAD96508 Q15257 EC
AK297202 BAG59687 B4DLX5  
AK302043 BAG63436 Q15257 EC
AK302897 BAG64070 B4DZF8  
X73478 CAA51873 Q15257 EC
CR749810 CAH18670 Q68CR8  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens PPP2R4 NP_066954 M.musculus Ppp2r4 110854 Gene Info NP_620087 96
R.norvegicus Ppp2r4 362102   NP_001102047 95
A.gambiae AgaP_AGAP008652 1275501   XP_314749 50
D.melanogaster Ptpa 33555   NP_523466 49
C.elegans Y71H2AM.20 175395   NP_497617 47
A.thaliana AT4G08960 826474   NP_567342 45
S.pombe SPAC1782.05 2542349   NP_594712 41
N.crassa NCU03269 3880571   XP_964422 40
S.cerevisiae RRD2 855951   NP_015173 38

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)