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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. ADH1B, alcohol dehydrogenase 1B (class I), beta polypeptide
Sequence ID:NM_000668
RefSeqGene ID:NG_011435
Entrez Gene ID:125
Ensembl ID:ENSG00000196616

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
ALCOHOL DEPENDENCEADH1C
GABRA2
HTR2A
RCBTB1
TAS2R16

Cytogenetic Location (from UniGene)

Cytogenetic Location:4q23Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:4: 100226122 - 100242556

NM_000668 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
91502100227527100229020
15031641100231921100232059
16421777100232677100232812
17782038100234977100235237
20392258100237054100237273
22592346100237371100237458
23472485100239202100239340
24862587100239941100240042
25882689100242470100242571

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4828235Full LengthBC033009alcohol dehydrogenase 1B (class I), beta polypeptide

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000659  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_000668 NP_000659   ADH_zinc_N
ADH_N

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
M21692 AAA51592 P00325 EC 1.1.1.1
M24317 AAA51884 P00325 EC 1.1.1.1
AF153821 AAD37446 P00325 EC 1.1.1.1
BC033009 AAH33009 P00325 EC 1.1.1.1
D00137 BAA00084 P00325 EC 1.1.1.1
AK299409 BAG61391 F5HB16  
AK301018 BAG62635 B4DVC3  
AK303945 BAG64873 B4E1R1  
AK304396 BAG65231 B4E2R9  
AK316501 BAH14872 B7ZB36  
X03350 CAA27056 P00325 EC 1.1.1.1

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens ADH1B NP_000659 A.thaliana ADH1 844047   NP_177837 52

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)