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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. PTK2, PTK2 protein tyrosine kinase 2
Sequence ID:NM_001199649
NM_005607
NM_153831
RefSeqGene ID:NG_029467
Entrez Gene ID:5747
Ensembl ID:ENSG00000169398

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, skin, soft tissue, spleen, stem cell, stomach, synovium, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:8q24.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:8: 141668503 - 142011318

 Exon Info From UCSC:
NM_005607
NM_153831

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4812915Full LengthBC028733PTK2 protein tyrosine kinase 2
4999680Full LengthBC035404PTK2 protein tyrosine kinase 2
3886095IncompleteBC015361PTK2 protein tyrosine kinase 2
5294745IncompleteBC043202PTK2 protein tyrosine kinase 2

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_722560  NP_005598  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_001199649 NP_001186578      
NM_005607 NP_005598 Q658W2   Focal_AT
Pkinase_Tyr
NM_153831 NP_722560 Q05397 EC 2.7.10.2 Focal_AT
Pkinase_Tyr

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
L13616 AAA58469 Q05397 EC 2.7.10.2
BC028733 AAH28733 I6L996  
BC035404 AAH35404 Q8IYN9  
EU176794 ABW03595    
AK094999 BAC04470 Q8N9D7  
AB209071 BAD92308 Q59GN8  
AB209083 BAD92320 Q59GM6  
AK294873 BAG57974 B4DH13  
AK301557 BAG63053 B4DWJ1  
AK304356 BAG65198 Q05397 EC 2.7.10.2
AL832961 CAH56296 Q658W2  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens PTK2 NP_005598 R.norvegicus Ptk2 25614   NP_037213 97
M.musculus Ptk2 14083 Gene Info NP_032008 97
A.gambiae AgaP_AGAP011118 1270807   XP_309528 45
D.melanogaster Fak56D 37233   NP_001137719 43
C.elegans kin-32 172135   NP_740841 36

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)