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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. SRD5A3, steroid 5 alpha-reductase 3
Sequence ID:NM_024592
RefSeqGene ID:NG_028230
Entrez Gene ID:79644
Ensembl ID:ENSG00000128039

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
CONGENITAL DISORDER OF GLYCOSYLATION, TYPE IQ 
KAHRIZI SYNDROME 

Cytogenetic Location (from UniGene)

Cytogenetic Location:4q12Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:4: 56212408 - 56237478

NM_024592 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
13165621240856212723
3174595622551256225654
4606575623024056230437
6587925623375456233888
79326605623599856237865

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3350037Full LengthBC002480steroid 5 alpha-reductase 3

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_078868  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_024592 NP_078868 Q9H8P0 EC 1.3.1.30
EC 1.3.1.94
Steroid_dh

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
BC002480 AAH02480 Q9H8P0 EC 1.3.1.30
EC 1.3.1.94
HQ447832 ADQ32316    
AK023414 BAB14568 Q9H8P0 EC 1.3.1.30
EC 1.3.1.94
CR457312 CAG33593 Q9H8P0 EC 1.3.1.30
EC 1.3.1.94

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens SRD5A3 NP_078868 M.musculus Srd5a3 57357 Gene Info NP_065636 81
R.norvegicus Srd5a3 305291   NP_001014012 81
A.gambiae AgaP_AGAP007493 1269733   XP_308382 32
D.melanogaster CG7840 34136   NP_609203 31
C.elegans B0024.13 179438   NP_001021341 29

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)