Skip Navigation
NCI banner National Cancer Institute U.S. National Institutes of Health National Cancer Institute
Genes
  • Gene Tools
Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. C8B, complement component 8, beta polypeptide
Sequence ID:NM_000066
RefSeqGene ID:NG_007285
Entrez Gene ID:732
Ensembl ID:ENSG00000021852

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
C8 DEFICIENCY, TYPE II 

Cytogenetic Location (from UniGene)

Cytogenetic Location:1p32Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:1: 57394976 - 57431668

 Exon Info From UCSC:
NM_000066

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
40146606Full LengthBC130575complement component 8, beta polypeptide
4723666IncompleteBC020701complement component 8, beta polypeptide

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000057  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_000066 NP_000057   Ldl_recept_a
TSP_1
MACPF

Related Sequences

 
mRNAGenPeptSwissProt
M16973 AAA51862 P07358
BC020701 AAH20701 Q05CV3
BC130575 AAI30576 P07358
HQ258464 ADR83218  
AK292740 BAF85429 A8K9M5
AK313382 BAG36180 P07358
AK298425 BAH12786 B7Z550
AK298444 BAH12791 B7Z555
AK316209 BAH14580 B7ZA94
X04393 CAA27981 P07358

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens C8B NP_000057 R.norvegicus C8b 313421   XP_233250 79
M.musculus C8b 110382 Gene Info NP_598643 76

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)