Skip Navigation
NCI banner National Cancer Institute U.S. National Institutes of Health National Cancer Institute
Genes
  • Gene Tools
Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. FYN, FYN oncogene related to SRC, FGR, YES
Sequence ID:NM_002037
NM_153047
NM_153048
NM_001242779
Entrez Gene ID:2534
Ensembl ID:ENSG00000010810

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, brain, cartilage, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, peripheral nervous system, pituitary gland, placenta, pooled tissue, retina, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:6q21Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:6: 111982941 - 112041254

 Exon Info From UCSC:
NM_002037
NM_153047
NM_153048

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
5219761Full LengthBC032496FYN oncogene related to SRC, FGR, YES

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_002028  NP_694593  NP_694592  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_002037 NP_002028 P06241 EC 2.7.10.2 SH2
SH3_1
Pkinase_Tyr
NM_153047 NP_694592     SH2
SH3_1
Pkinase_Tyr
NM_153048 NP_694593     SH2
SH3_1
Pkinase_Tyr

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
M14676 AAA36615 P06241 EC 2.7.10.2
S74774 AAB33113 P06241 EC 2.7.10.2
M14333 AAC08285 P06241 EC 2.7.10.2
BC032496 AAH32496 P06241 EC 2.7.10.2
JF432194 ADZ15411    
AK056699 BAG51788 B3KPS6  
AB451293 BAG70107 P06241 EC 2.7.10.2
AB451426 BAG70240 P06241 EC 2.7.10.2

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens FYN NP_002028 R.norvegicus Fyn 25150   NP_036887 100
M.musculus Fyn 14360 Gene Info NP_001116365 99
C.elegans src-1 171722   NP_490866 52

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta