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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. MAP3K4, mitogen-activated protein kinase kinase kinase 4
Sequence ID:NM_005922
NM_006724
Entrez Gene ID:4216
Ensembl ID:ENSG00000085511

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Cytogenetic Location (from UniGene)

Cytogenetic Location:6q26Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:6: 161412821 - 161538381

 Exon Info From UCSC:
NM_005922
NM_006724

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
9007216Full LengthBC146770mitogen-activated protein kinase kinase kinase 4
9020263Full LengthBC136276mitogen-activated protein kinase kinase kinase 4
9052249Full LengthBC143735mitogen-activated protein kinase kinase kinase 4

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_005913  NP_006715  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_005922 NP_005913   Pkinase
Pkinase_Tyr
NM_006724 NP_006715   Pkinase
Pkinase_Tyr

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
AF002715 AAB68804 Q9Y6R4 EC 2.7.11.25
AF116604 AAF71029 Q9P1M2  
BC136276 AAI36277 Q9Y6R4 EC 2.7.11.25
BC143735 AAI43736 Q9Y6R4 EC 2.7.11.25
BC146770 AAI46771 Q9Y6R4 EC 2.7.11.25
D86968 BAA13204 Q9Y6R4 EC 2.7.11.25

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens MAP3K4 NP_005913 R.norvegicus Map3k4 308106   NP_001100926 91
M.musculus Map3k4 26407 Gene Info NP_036078 89
A.gambiae AgaP_AGAP002371 1273592   XP_312585 39
D.melanogaster Mekk1 42253   NP_732373 36

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta