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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. XRCC5, X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
Sequence ID:NM_021141
RefSeqGene ID:NG_029780
Entrez Gene ID:7520
Ensembl ID:ENSG00000079246

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pineal gland, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:2q35Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:2: 217060459 - 217062171

 Exon Info From UCSC:
NM_021141

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4555162Full LengthBC019027X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
30329657Full LengthBC095442X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_066964  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_021141 NP_066964 P13010 Ku
Ku_C
Ku_N

Related Sequences

 
mRNAGenPeptSwissProt
M30938 AAA36154 P13010
J04977 AAA59475 P13010
BC019027 AAH19027 P13010
BC095442 AAH95442 P13010
DQ892660 ABM83586  
DQ895925 ABM86851  
AK222603 BAD96323 P13010
AK290740 BAF83429 P13010
X57500 CAA40736 P13010

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens XRCC5 NP_066964 M.musculus Xrcc5 22596 Gene Info NP_033559 79
R.norvegicus Xrcc5 363247   NP_803154 78
A.gambiae AgaP_AGAP009910 1279324   XP_319031 31
A.thaliana KU80 841223   NP_564520 29
N.crassa NCU00077 3872525   XP_956387 29
S.pombe pku80 2541045   NP_596791 24

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta