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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. ACLY, ATP citrate lyase
Sequence ID:NM_001096
NM_198830
Entrez Gene ID:47
Ensembl ID:ENSG00000131473

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, peripheral nervous system, pineal gland, placenta, pooled tissue, prostate, retina, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:17q21.2Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:17: 40023169 - 40075215

 Exon Info From UCSC:
NM_001096
NM_198830

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
2959339Full LengthBC006195ATP citrate lyase

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_001087  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_001096 NP_001087 P53396 EC 2.3.3.8 Ligase_CoA
CoA_binding
NM_198830 NP_942127      

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
U18197 AAB60340 P53396 EC 2.3.3.8
BC006195 AAH06195 P53396 EC 2.3.3.8
JF432308 ADZ15525    
AK095084 BAC04484 Q8N9C4  
AB210035 BAE06117 Q4LE36  
AK295675 BAG58532 P53396 EC 2.3.3.8
AK304802 BAG65552 B4E3P0  
X64330 CAA45614 P53396 EC 2.3.3.8

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens ACLY NP_001087 M.musculus Acly 104112 Gene Info NP_598798 98
R.norvegicus Acly 24159   NP_058683 98
A.gambiae AgaP_AGAP010156 1279572   XP_319323 70
D.melanogaster ATPCL 36760   NP_725514 70
S.pombe SPBC1703.07 2539879   NP_596202 65
N.crassa NCU06785 3879766   XP_963626 64
C.elegans B0365.1 179795   NP_506267 63
C.elegans D1005.1 180485   NP_508280 62
A.thaliana ACLB-1 819845   NP_187317 54
A.thaliana ACLB-2 835006   NP_199757 53

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta