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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. LCAT, lecithin-cholesterol acyltransferase
Sequence ID:NM_000229
RefSeqGene ID:NG_009778
Entrez Gene ID:3931
Ensembl ID:ENSG00000213398

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
FISH-EYE DISEASE 
NORUM DISEASE 

Cytogenetic Location (from UniGene)

Cytogenetic Location:16q22.1Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:16: 67972912 - 67974738

NM_000229 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
15956797378667974380
5968206797626567976489
8219166797657367976668
91710326797676367976878
103311896797695867977114
119013546797785067978014

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4155094Full LengthBC014781lecithin-cholesterol acyltransferase

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000220  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_000229 NP_000220 P04180 EC 2.3.1.43 LACT

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
M12625 AAA59498 P04180 EC 2.3.1.43
M26268 AAA59499 P04180 EC 2.3.1.43
BC014781 AAH14781 P04180 EC 2.3.1.43
BT009748 AAP88750 P04180 EC 2.3.1.43
X06537 CAB56610 P04180 EC 2.3.1.43

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens LCAT NP_000220 R.norvegicus Lcat 24530   NP_058720 87
M.musculus Lcat 16816 Gene Info NP_032516 86

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)