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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. CDK8, cyclin-dependent kinase 8
Sequence ID:NM_001260
Entrez Gene ID:1024
Ensembl ID:ENSG00000132964

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Cytogenetic Location (from UniGene)

Cytogenetic Location:13q12Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:13: 26956966 - 26978540

 Exon Info From UCSC:
NM_001260

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
7262421Full LengthBC069634cyclin-dependent kinase 8
40032849Full LengthBC107601cyclin-dependent kinase 8
40032852Full LengthBC105950cyclin-dependent kinase 8
40032854Full LengthBC104492cyclin-dependent kinase 8

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_001251  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_001260 NP_001251 P49336 EC 2.7.11.23
EC 2.7.11.22
Pkinase

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
BC069634 AAH69634 P49336 EC 2.7.11.23
EC 2.7.11.22
BC104492 AAI04493 P49336 EC 2.7.11.23
EC 2.7.11.22
BC105950 AAI05951 P49336 EC 2.7.11.23
EC 2.7.11.22
BC107601 AAI07602 P49336 EC 2.7.11.23
EC 2.7.11.22
AY702976 AAU29339 Q64FY6  
AK296084 BAG58839 B4DJH7  
AK296875 BAG59437 B4DL75  
X85753 CAA59754 P49336 EC 2.7.11.23
EC 2.7.11.22

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens CDK8 NP_001251 M.musculus Cdk8 264064 Gene Info NP_705827 99
A.gambiae AgaP_AGAP009936 1279351   XP_319061 88
D.melanogaster Cdk8 39157   NP_536735 85
C.elegans cdk-8 172677   NP_492357 63

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta