Skip Navigation
NCI banner National Cancer Institute U.S. National Institutes of Health National Cancer Institute
Genes
  • Gene Tools
Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. DEFA1, defensin, alpha 1
Sequence ID:NM_004084
Entrez Gene ID:1667
Ensembl ID:ENSG00000206047

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data


Cytogenetic Location (from UniGene)

Cytogenetic Location:8p23.1Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:8: 6835241 - 6837572

NM_004084 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
1724768351706835400
24843468359816836167
43551468375346837613

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
7262694Full LengthBC069423defensin, alpha 1
7939636Full LengthBC093791defensin, alpha 1
8327656Full LengthBC112188defensin, alpha 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_004075  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_001042500 NP_001035965    
NM_004084 NP_004075 P59665 Defensin_1
Defensin_propep

Related Sequences

 
mRNAGenPeptSwissProt
M21130 AAA52302 P59665
M26602 AAA52303 P59665
BC069423 AAH69423 P59665
BC093791 AAH93791 P59665
BC112188 AAI12189 P59665
DQ896798 ABM87797  
DQ890545 ABM92162  
DQ890546 ABM92163  
HQ448386 ADQ32866  
X52053 CAA36280 P59665

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens DEFA1 NP_004075 H.sapiens DEFA1B 728358   NP_001035965 100
H.sapiens DEFA3 1668 Gene Info NP_005208 99

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)