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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. OGG1, 8-oxoguanine DNA glycosylase
Sequence ID:NM_002542
NM_016819
NM_016820
NM_016821
NM_016826
NM_016827
NM_016828
NM_016829
RefSeqGene ID:NG_012106
Entrez Gene ID:4968
Ensembl ID:ENSG00000114026

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
RENAL CARCINOMA, CHROMOPHOBE, SOMATICDIRC2
FLCN
HNF1A
HNF1B
RNF139
VHL

Cytogenetic Location (from UniGene)

Cytogenetic Location:3p26.2Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:3: 9791707 - 9799087

 Exon Info From UCSC:
NM_002542
NM_016819
NM_016820
NM_016821
NM_016826
NM_016827
NM_016828
NM_016829

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3350168Full LengthBC0006578-oxoguanine DNA glycosylase

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_058438  NP_058212  NP_058436  NP_002533  NP_058437  NP_058213  NP_058214  NP_058434  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_002542 NP_002533 O15527 EC 4.2.99.18 HHH
HhH-GPD
OGG_N
NM_016819 NP_058212     HHH
HhH-GPD
OGG_N
NM_016820 NP_058213     HHH
HhH-GPD
OGG_N
NM_016821 NP_058214     HHH
HhH-GPD
OGG_N
NM_016826 NP_058434     HhH-GPD
OGG_N
NM_016827 NP_058436     HhH-GPD
OGG_N
NM_016828 NP_058437     HHH
HhH-GPD
OGG_N
NM_016829 NP_058438     HHH
HhH-GPD
OGG_N

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
AF003595 AAB61340 O15527 EC 4.2.99.18
U88527 AAB68614 O15527 EC 4.2.99.18
U88620 AAB68615 O15527 EC 4.2.99.18
U96710 AAB81132 O15527 EC 4.2.99.18
AF026691 AAB84013 O15527 EC 4.2.99.18
BC000657 AAH00657 O15527 EC 4.2.99.18
DQ896107 ABM87106    
EU176392 ABW03843    
AB000410 BAA19103 O15527 EC 4.2.99.18
AB019528 BAA76635 O15527 EC 4.2.99.18
AB019529 BAA76636 O15527 EC 4.2.99.18
AB019530 BAA76637 O15527 EC 4.2.99.18
AB019531 BAA76638 O15527 EC 4.2.99.18
AB019532 BAA76639 O15527 EC 4.2.99.18
AB037878 BAB13293 Q9GZT7  
AB037879 BAB13294 Q9HCR8  
AB037880 BAB13295 Q9HCR7  
AB037881 BAB13296 Q9HCR6  
AB037882 BAB13297 Q9GZT7  
AK289858 BAF82547 O15527 EC 4.2.99.18
Y11731 CAA72414 O15527 EC 4.2.99.18
Y11838 CAA72536 O15527 EC 4.2.99.18
Y13277 CAA73726 O15527 EC 4.2.99.18

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens OGG1 NP_002533 M.musculus Ogg1 18294 Gene Info NP_035087 85
R.norvegicus Ogg1 81528   NP_110497 85
A.gambiae AgaP_AGAP001854 1281270   XP_321213 46
N.crassa NCU03040 3880194   XP_964045 46
S.cerevisiae OGG1 854942   NP_013651 43
A.thaliana OGG1 838775   NP_173590 42
D.melanogaster Ogg1 31806   NP_572499 37

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)