Skip Navigation
NCI banner National Cancer Institute U.S. National Institutes of Health National Cancer Institute
Genes
  • Gene Tools
Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. CAD, carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
Sequence ID:NM_004341
Entrez Gene ID:790
Ensembl ID:ENSG00000084774

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, peripheral nervous system, placenta, pooled tissue, prostate, retina, skin, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:2p22-p21Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:2: 27440339 - 27445488

 Exon Info From UCSC:
NM_004341

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
5551082Full LengthBC065510carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
4580779IncompleteBC014178carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_004332  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_004341 NP_004332 P27708 EC 3.5.2.3
EC 6.3.5.5
EC 2.1.3.2
GATase
OTCace
CPSase_L_chain
CPSase_sm_chain
Amidohydro_1
MGS
OTCace_N
CPSase_L_D2
CPSase_L_D3

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
BC014178 AAH14178 Q96CK3  
BC065510 AAH65510 P27708 EC 3.5.2.3
EC 6.3.5.5
EC 2.1.3.2
D78586 BAA11423 P27708 EC 3.5.2.3
EC 6.3.5.5
EC 2.1.3.2
AB621827 BAK64162 G1UI39  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens CAD NP_004332 M.musculus Cad 69719 Gene Info NP_076014 95
R.norvegicus Cad 24240   NP_001099180 95
A.gambiae AgaP_AGAP000300 1271961   XP_310823 66
D.melanogaster r 32640   NP_523377 66
C.elegans pyr-1 174385   NP_495838 59
N.crassa NCU08287 3877961   XP_961813 59
S.cerevisiae URA2 853311   NP_012405 53
S.pombe ura1 2541544   NP_593055 53
P.falciparum cpsSII 814023   XP_001349809 51
A.thaliana CARB 839868   NP_564338 43

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)