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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. SOX10, SRY (sex determining region Y)-box 10
Sequence ID:NM_006941
RefSeqGene ID:NG_007948
Entrez Gene ID:6663
Ensembl ID:ENSG00000100146

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
PCWH SYNDROME 
WAARDENBURG SYNDROME, TYPE 4AEDN3
EDNRB
WAARDENBURG SYNDROME, TYPE 4C 
WAARDENBURG SYNDROME,TYPE 2E, WITH OR WITHOUT NEUROLOGIC INVOLVEMENT 

Cytogenetic Location (from UniGene)

Cytogenetic Location:22q13.1Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:22: 38368474 - 38380376

NM_006941 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
2119073836831838370204
190821763837387338374141
217726883837936338379874
268928823838034538380538

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3346551Full LengthBC007595SRY (sex determining region Y)-box 10
3635492Full LengthBC002824SRY (sex determining region Y)-box 10

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_008872  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_006941 NP_008872 P56693 HMG_box

Related Sequences

 
mRNAGenPeptSwissProt
BC002824 AAH02824 P56693
BC007595 AAH07595 P56693
BT020029 AAV38832 P56693
DQ893172 ABM84098  
DQ896471 ABM87470  
AK300945 BAG62574 B4DV62
AJ001183 CAA04576 P56693
CR456584 CAG30470 P56693
CR536571 CAG38808 Q6FHW7
CU013183 CAK54614  
CU013471 CAK54913  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens SOX10 NP_008872 M.musculus Sox10 20665 Gene Info NP_035567 98
R.norvegicus Sox10 29361   NP_062066 97

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)