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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. MFN2, mitofusin 2
Sequence ID:NM_001127660
NM_014874
RefSeqGene ID:NG_007945
Entrez Gene ID:9927
Ensembl ID:ENSG00000116688

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes
CHARCOT-MARIE-TOOTH DISEASE, TYPE 2A2 
HEREDITARY MOTORAND SENSORY NEUROPATHY VI 

Cytogenetic Location (from UniGene)

Cytogenetic Location:1p36.22Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:1: 12040368 - 12073565

 Exon Info From UCSC:
NM_001127660
NM_014874

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3901235Full LengthBC017061mitofusin 2

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_055689  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_001127660 NP_001121132    
NM_014874 NP_055689 O95140 Dynamin_N
Fzo_mitofusin

Related Sequences

 
mRNAGenPeptSwissProt
AF036536 AAD02058 O95140
BC017061 AAH17061 O95140
AY028429 AAK18728 O95140
DQ894181 ABM85107  
EU176270 ABW03721  
D86987 BAA34389 O95140
AK289828 BAF82517 O95140
AK001189 BAG50864 B3KM52
AK021947 BAG51062 A6NLD2
AK022453 BAG51075 B3KMR3
AK295890 BAH12214 B7Z3H8
AL137666 CAB70866 O95140

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens MFN2 NP_001121132 R.norvegicus Mfn2 64476   NP_570964 96
M.musculus Mfn2 170731 Gene Info NP_573464 95
A.gambiae AgaP_AGAP001802 1281313   XP_321258 50
D.melanogaster Marf 31581   NP_572320 49
C.elegans fzo-1 173990   NP_495161 37

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)