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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. SYK, spleen tyrosine kinase
Sequence ID:NM_001135052
NM_001174167
NM_001174168
NM_003177
RefSeqGene ID:NG_017046
Entrez Gene ID:6850
Ensembl ID:ENSG00000165025

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Cytogenetic Location (from UniGene)

Cytogenetic Location:9q22Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:9: 93660235 - 93660831

 Exon Info From UCSC:
NM_001135052
NM_001174167
NM_001174168
NM_003177

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
2959066Full LengthBC001645spleen tyrosine kinase
3542895Full LengthBC002962spleen tyrosine kinase
3870426Full LengthBC011399spleen tyrosine kinase

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_003168  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_001135052 NP_001128524      
NM_001174167 NP_001167638      
NM_001174168 NP_001167639      
NM_003177 NP_003168 P43405 EC 2.7.10.2 SH2
Pkinase_Tyr

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
L28824 AAA36526 P43405 EC 2.7.10.2
S80267 AAB35601 Q13196  
BC001645 AAH01645 P43405 EC 2.7.10.2
BC002962 AAH02962 P43405 EC 2.7.10.2
BC011399 AAH11399 P43405 EC 2.7.10.2
AK290927 BAF83616 A8K4G2  
AK075020 BAG52053 B3KQJ1  
X73568 CAA51970 P43405 EC 2.7.10.2
Z29630 CAA82737 P43405 EC 2.7.10.2
FN391891 CAY55929 C3W980  
FN391892 CAY55930 C3W981  
FN391893 CAY55931 C3W980  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens SYK NP_003168 M.musculus Syk 20963 Gene Info NP_035648 93
R.norvegicus Syk 25155   NP_036890 92

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta