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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. MKNK1, MAP kinase interacting serine/threonine kinase 1
Sequence ID:NM_001135553
NM_003684
NM_198973
NR_024174
NR_024176
NR_024175
RefSeqGene ID:NG_032029
Entrez Gene ID:8569
Ensembl ID:ENSG00000079277

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Cytogenetic Location (from UniGene)

Cytogenetic Location:1p33Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:1: 47023090 - 47069909

 Exon Info From UCSC:
NM_001135553
NM_003684
NM_198973

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3629765Full LengthBC002755MAP kinase interacting serine/threonine kinase 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_003675  NP_945324  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_001135553 NP_001129025      
NM_003684 NP_003675 Q9BUB5 EC 2.7.11.1 Pkinase
NM_198973 NP_945324     Pkinase

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
BC002755 AAH02755 Q9BUB5 EC 2.7.11.1
AY355461 AAQ84219 Q9BUB5 EC 2.7.11.1
DQ892992 ABM83918    
DQ896240 ABM87239    
EU831709 ACE86543    
EU831624 ACE87224    
AB000409 BAA19885 Q9BUB5 EC 2.7.11.1
AK290456 BAF83145 A8K341  
AK096423 BAG53286 B3KU24  
AK298839 BAG60967 B4DQK5  
AK304005 BAG64921 B4E1V9  
AB451300 BAG70114 B5BU64  
AB451432 BAG70246 B5BUJ6  
BX538193 CAD98062 Q7Z319  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens MKNK1 NP_003675 R.norvegicus Mknk1 500526   NP_001037732 95
M.musculus Mknk1 17346 Gene Info NP_067436 94
D.melanogaster Lk6 44672   NP_651986 54
C.elegans mnk-1 174623   NP_871924 49

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta