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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. PON1, paraoxonase 1
Sequence ID:NM_000446
RefSeqGene ID:NG_008779
Entrez Gene ID:5444
Ensembl ID:ENSG00000005421

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
MICROVASCULAR COMPLICATIONS OF DIABETES 5 

Cytogenetic Location (from UniGene)

Cytogenetic Location:7q21.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:7: 94928255 - 94953808

NM_000446 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
207639492767094928413
7648929493151694931644
8939749493559694935677
97511759493732294937522
117613029494076294940888
130314719494463394944801
147215279494604594946100
152815989494763494947704
159917699495371394953883

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
30915169Full LengthBC074719paraoxonase 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000437  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_000446 NP_000437 P27169 EC 3.1.8.1
EC 3.1.1.2
EC 3.1.1.81
Arylesterase

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
M63013 AAA60142 P27169 EC 3.1.8.1
EC 3.1.1.2
EC 3.1.1.81
M63014 AAA60143 P27169 EC 3.1.8.1
EC 3.1.1.2
EC 3.1.1.81
U53784 AAA97957 P27169 EC 3.1.8.1
EC 3.1.1.2
EC 3.1.1.81
S64615 AAB27714 P27169 EC 3.1.8.1
EC 3.1.1.2
EC 3.1.1.81
M63012 AAB59538 P27169 EC 3.1.8.1
EC 3.1.1.2
EC 3.1.1.81
BC074719 AAH74719 P27169 EC 3.1.8.1
EC 3.1.1.2
EC 3.1.1.81
D84371 BAA12327 P27169 EC 3.1.8.1
EC 3.1.1.2
EC 3.1.1.81
AK314027 BAG36737 P27169 EC 3.1.8.1
EC 3.1.1.2
EC 3.1.1.81
Z70723 CAA94728 P27169 EC 3.1.8.1
EC 3.1.1.2
EC 3.1.1.81

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens PON1 NP_000437 M.musculus Pon1 18979 Gene Info NP_035264 82
R.norvegicus Pon1 84024   NP_114466 81

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)