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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. XPO1, exportin 1 (CRM1 homolog, yeast)
Sequence ID:NM_003400
Entrez Gene ID:7514
Ensembl ID:ENSG00000082898

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pineal gland, pituitary gland, placenta, pooled tissue, prostate, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:2p15Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:2: 61709759 - 61715798

 Exon Info From UCSC:
NM_003400

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
5267242Full LengthBC032847exportin 1 (CRM1 homolog, yeast)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_003391  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_003400 NP_003391 O14980 IBN_N
Xpo1

Related Sequences

 
mRNAGenPeptSwissProt
BC032847 AAH32847 O14980
DQ891271 ABM82197  
D89729 BAA23415 O14980
AK289920 BAF82609 O14980
AK124769 BAG54092 B3KWD0
AK299039 BAG61113 B4DR01
AK316481 BAH14852 B7ZB16
Y08614 CAA69905 O14980
CR749840 CAH18695 O14980
BX647758 CAH56174 O14980

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens XPO1 NP_003391 M.musculus Xpo1 103573 Gene Info NP_001030303 98
R.norvegicus Xpo1 85252   NP_445942 98
A.gambiae AgaP_AGAP009929 1279344   XP_319051 73
D.melanogaster emb 34167   NP_723391 71
S.pombe crm1 3361487   NP_001018253 55
N.crassa NCU01820 3872064   XP_955917 54
C.elegans xpo-1 179160   NP_741567 53
A.thaliana XPO1B 821074   NP_566193 50
A.thaliana XPO1A 831565   NP_197204 50
S.cerevisiae CRM1 853133   NP_011734 48

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta