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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. FOXO1, forkhead box O1
Sequence ID:NM_002015
RefSeqGene ID:NG_023244
Entrez Gene ID:2308
Ensembl ID:ENSG00000150907

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, placenta, pooled tissue, prostate, retina, skin, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes
RHABDOMYOSARCOMA 2, ALVEOLARPAX3
PAX7

Cytogenetic Location (from UniGene)

Cytogenetic Location:13q14.1Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:13: 41129816 - 41240734

NM_002015 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
333714112980241133170
337247234113364541134996
472457384123971941240733

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
2959021Full LengthBC021981forkhead box O1
30345006Full LengthBC070065forkhead box O1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_002006  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_002015 NP_002006 Q12778 Fork_head

Related Sequences

 
mRNAGenPeptSwissProt
U02310 AAA03629 Q12778
AF032885 AAC39591 Q12778
BC021981 AAH21981 Q12778
BC070065 AAH70065 Q12778
BT007455 AAP36123 Q12778

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens FOXO1 NP_002006 M.musculus Foxo1 56458 Gene Info NP_062713 94
R.norvegicus Foxo1 84482   XP_342245 93

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta