Skip Navigation
NCI banner National Cancer Institute U.S. National Institutes of Health National Cancer Institute
Genes
  • Gene Tools
Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. FNTA, farnesyltransferase, CAAX box, alpha
Sequence ID:NM_002027
NR_033698
NM_001018676
NM_001018677
Entrez Gene ID:2339
Ensembl ID:ENSG00000168522

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, bone marrow, brain, cartilage, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pineal gland, pituitary gland, placenta, pooled tissue, prostate, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:8p11Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:8: 42911815 - 42940923

Transcript StartTranscript EndChromosomal Start Chromosomal End
12484291144142911688
2493344291423442914319
3354494291924342919357
4505544292469742924801
5556814292732342927449
6828304293235842932506
8318934293826042938322
89410654293985242940023
106616864294030242940922

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
6423445Full LengthBC084566farnesyltransferase, CAAX box, alpha
3850453IncompleteBC017029farnesyltransferase, CAAX box, alpha

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_002018  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_002027 NP_002018 P49354 EC 2.5.1.59
EC 2.5.1.58
PPTA

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
L00634 AAA35853 P49354 EC 2.5.1.59
EC 2.5.1.58
L10413 AAA86285 P49354 EC 2.5.1.59
EC 2.5.1.58
BC017029 AAH17029 P49354 EC 2.5.1.59
EC 2.5.1.58
BC084566 AAH84566 P49354 EC 2.5.1.59
EC 2.5.1.58
BT009854 AAP88856 P49354 EC 2.5.1.59
EC 2.5.1.58
AB209689 BAD92926 Q59EX2  
AK292121 BAF84810 P49354 EC 2.5.1.59
EC 2.5.1.58
AK123002 BAG53844 B3KVN2  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens FNTA NP_002018 M.musculus Fnta 14272 Gene Info NP_032059 93
R.norvegicus Fnta 25318   NP_036979 93
A.gambiae AgaP_AGAP011767 1280873   XP_320743 53
D.melanogaster CG2976 33682   NP_608862 50
A.thaliana FTA 825107   NP_567084 45
C.elegans R02D3.5 176840   NP_499882 41
S.pombe cwp1 2543143   NP_593518 38
N.crassa NCU03632 3877482   XP_961359 35
S.cerevisiae RAM2 853849   NP_012906 30

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)