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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. TYMS, thymidylate synthetase
Sequence ID:NM_001071
RefSeqGene ID:NG_028255
Entrez Gene ID:7298
Ensembl ID:ENSG00000176890

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Cytogenetic Location (from UniGene)

Cytogenetic Location:18p11.32Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:18: 657633 - 673499

NM_001071 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
1344657603657946
345418659640659713
419593662145662319
594695669071669172
696871670691670866
872943671379671450
9441583672859673498

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3138877Full LengthBC002567thymidylate synthetase
4048625Full LengthBC013919thymidylate synthetase
4299083Full LengthBC083512thymidylate synthetase

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_001062  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_001071 NP_001062 Q53Y97
P04818
EC 2.1.1.45 Thymidylat_synt

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
BC002567 AAH02567 Q53Y97
P04818
EC 2.1.1.45
BC013919 AAH13919 Q53Y97
P04818
EC 2.1.1.45
BC083512 AAH83512 Q53Y97
P04818
EC 2.1.1.45
BT006811 AAP35457 Q53Y97
P04818
EC 2.1.1.45
DQ892149 ABM83075    
AB077207 BAB83676 Q8WYK4  
AB077208 BAB83677 Q8WYK3  
AB062290 BAB93473 Q53Y97
P04818
EC 2.1.1.45
AK223372 BAD97092 Q53FB7  
AK292620 BAF85309 A8K9A5  
AK314140 BAG36830 Q53Y97  
X02308 CAA26178 Q53Y97
P04818
EC 2.1.1.45

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens TYMS NP_001062 M.musculus Tyms 22171 Gene Info NP_067263 91
R.norvegicus Tyms 29261   NP_062052 89
C.elegans Y110A7A.4 172149   NP_491532 68
A.gambiae AgaP_AGAP010457 1272582   XP_311491 67
A.thaliana THY-2 829609   NP_195183 66
A.thaliana THY-1 816134   NP_179230 65
D.melanogaster Ts 33499   NP_477367 65
S.cerevisiae CDC21 854241   NP_014717 65
N.crassa NCU10053 3874088   XP_957941 63
S.pombe SPAC15E1.04 2542801   NP_594305 61
P.falciparum PFD0805w 812524   XP_001351479 56
A.thaliana AT2G21550 816694   NP_179750 47

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)