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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. IRAK3, Interleukin-1 receptor-associated kinase 3
Sequence ID:NM_007199
NM_001142523
RefSeqGene ID:NG_021194
Entrez Gene ID:11213
Ensembl ID:ENSG00000090376

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
ASTHMA SUSCEPTIBILITY 5 

Cytogenetic Location (from UniGene)

Cytogenetic Location:12q14.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:12: 66583016 - 66642385

 Exon Info From UCSC:
NM_007199
NM_001142523

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
7262303Full LengthBC069388interleukin-1 receptor-associated kinase 3
30335802Full LengthBC057800interleukin-1 receptor-associated kinase 3

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_009130  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_001142523 NP_001135995      
NM_007199 NP_009130 Q9Y616 EC 2.7.11.1 Pkinase
Death

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
AF113136 AAD40879 Q9Y616 EC 2.7.11.1
BC057800 AAH57800 Q9Y616 EC 2.7.11.1
BC069388 AAH69388 Q9Y616 EC 2.7.11.1
JF432379 ADZ15596    
AK314040 BAG36749 B2RA52  
AK298645 BAG60819 Q9Y616 EC 2.7.11.1

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens IRAK3 NP_009130 R.norvegicus Irak3 314870   NP_001101571 77
M.musculus Irak3 73914 Gene Info NP_082955 76

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta