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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. SORL1, sortilin-related receptor, L(DLR class) A repeats containing
Sequence ID:NM_003105
RefSeqGene ID:NG_023313
Entrez Gene ID:6653
Ensembl ID:ENSG00000137642

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, retina, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes
ALZHEIMER DISEASEA2M
ACE
APBB2
APP
BLMH
HFE
MPO
NOS3
PAXIP1
PLAU

Cytogenetic Location (from UniGene)

Cytogenetic Location:11q23.2-q24.2Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:11: 121501768 - 121504397

 Exon Info From UCSC:
NM_003105

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
9021168Full LengthBC137171sortilin-related receptor, L(DLR class) A repeats-containing

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_003096  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_003105 NP_003096 Q92673 fn3
Ldl_recept_a
Ldl_recept_b
BNR

Related Sequences

 
mRNAGenPeptSwissProt
BC137171 AAI37172 Q92673
AK294404 BAG57656 B4DG45
AK295090 BAG58131 B4DHG9
AK295878 BAG58675 B4DJ13
AK302589 BAG63842 B4DYT0
AK316340 BAH14711 B4DG45
Y08110 CAA69325 Q92673

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens SORL1 NP_003096 M.musculus Sorl1 20660 Gene Info NP_035566 93
A.gambiae AgaP_AGAP010896 1271050   XP_309795 38

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)