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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. SMPD3, sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)
Sequence ID:NM_018667
Entrez Gene ID:55512
Ensembl ID:ENSG00000103056

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Cytogenetic Location (from UniGene)

Cytogenetic Location:16q22.1Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:16: 68395108 - 68406084

NM_018667 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
329816839223168395209
298231386839550568395661
313932026839739868397461
320332926839767968397768
329334486839865368398808
344935246839891968398994
352550536840476168406289
505451156842050068420561
511652696848225568482408

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
8327706Full LengthBC112238sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)
3938320IncompleteBC012727sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)
5267985IncompleteBC041828sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_061137  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_018667 NP_061137 Q9NY59 EC 3.1.4.12 Exo_endo_phos

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
BC112238 AAI12239 Q9NY59 EC 3.1.4.12
BC143631 AAI43632 B7ZL82  
BC143634 AAI43635 B7ZL84  
DQ424899 ABD83664 Q1ZYL9  
HQ258353 ADR83107    
AK026246 BAB15409 Q9H657  
AK289651 BAF82340 A8K0T6  
AJ250460 CAB92964 Q9NY59 EC 3.1.4.12
XM_001723709 XP_001723761    
XM_001726630 XP_001726682    

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens SMPD3 NP_061137 M.musculus Smpd3 58994 Gene Info NP_067466 92
R.norvegicus Smpd3 94338   NP_446057 91

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)