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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. HGD, homogentisate 1,2-dioxygenase
Sequence ID:NM_000187
RefSeqGene ID:NG_011957
Entrez Gene ID:3081
Ensembl ID:ENSG00000113924

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
ALKAPTONURIA 

Cytogenetic Location (from UniGene)

Cytogenetic Location:3q13.33Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:3: 120347019 - 120401125

 Exon Info From UCSC:
NM_000187

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4716316Full LengthBC020792homogentisate 1,2-dioxygenase (homogentisate oxidase)
6714217Full LengthBC071757homogentisate 1,2-dioxygenase (homogentisate oxidase)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000178  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_000187 NP_000178 Q93099 EC 1.13.11.5 HgmA

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
U63008 AAB16836 Q93099 EC 1.13.11.5
AF045167 AAC02698 Q93099 EC 1.13.11.5
BC020792 AAH20792 Q8WW71  
BC071757 AAH71757 Q93099 EC 1.13.11.5
EU831690 ACE86524    
EU831603 ACE87203    
HQ447586 ADQ32072    
AK290782 BAF83471 A8K417  
AK313563 BAG36337 Q93099 EC 1.13.11.5
AK124291 BAG54026 B3KW64  
Z75048 CAA99340 Q93099 EC 1.13.11.5

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens HGD NP_000178 M.musculus Hgd 15233 Gene Info NP_038575 93
R.norvegicus Hgd 360719   NP_001012145 91
A.gambiae AgaP_AGAP009609 1278983   XP_318638 67
D.melanogaster hgo 34552   NP_523544 67
C.elegans hgo-1 172726   NP_492433 67
A.thaliana HGO 835494   NP_200219 60
N.crassa NCU05499 3876615   XP_960461 54

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)